Heritability of clubfoot: a twin study

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Heritability of clubfoot: a twin study

INTRODUCTION The aetiology of congenital clubfoot is unclear. Although studies on populations, families, and twins suggest a genetic component to the aetiology, other studies have identified environmental factors. The purpose of this study was to calculate heritability in order to determine to what extent genetic and/or environmental factors contribute to the aetiology of congenital clubfoot an...

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PURPOSE Several studies have reported higher levels of macular pigment (MP) in association with reduced risk for age-related macular degeneration (ARMD), a disease to which there is a genetic predisposition. A classic twin study was performed to determine the heritability of MP in the healthy eye. METHODS One hundred fifty twin pairs (76 monozygotic [MZ] and 74 dizygotic [DZ]), aged 18 to 50 ...

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The authors administered inventories of vocational and recreational interests and talents to 924 pairs of twins who had been reared together and to 92 pairs separated in infancy and reared apart. Factor analysis of all 291 items yielded 39 identifiable factors and 11 superfactors. The data indicated that about 50% of interests variance (about two thirds of the stable variance) was associated wi...

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Heritability of cilioretinal arteries: a twin study.

PURPOSE To determine whether the presence of one or more cilioretinal arteries, a distinct element of the pattern of fundus vessels, is genetically programmed, influenced by environmental factors, or the result of random mechanisms of vascular development. METHODS The fundi of 112 pairs of healthy monozygotic and dizygotic twins were examined using digital fundus photography and visual assess...

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ژورنال

عنوان ژورنال: Journal of Children's Orthopaedics

سال: 2014

ISSN: 1863-2521,1863-2548

DOI: 10.1007/s11832-014-0562-7